when playing minecraft on my Macbook (creative or survival) the keyboard will occasionally become unresponsive. No keys will work, I can still look around, but I can not move, open the inventory, chat, or pause screen. This freeze can last between 10 seconds, up to 45+ seconds.
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Try the new launcher https://mojang.com/2013/06/minecraft-snapshot-13w25a/ with version 1.5.2 , there are major updates of system near libraries.