Repro steps:
Launch Unified Launcher.
Sign in with MSA/MJA Production with MC Java entitlements.
Go to 'Installations', select 'edit' on the latest release version and set the resolution to the 2560x1440.
Launch Minecraft Java on the latest release build.
Hover over any options available.
Observed results:
Mouse cursor position is not correctly selecting the correct option on hover while the User is using the highest resolution (2560x1440).
Expected results:
Mouse cursor position is correctly selecting the correct option on hover on all resolutions.
I was unable to reproduce in 21w16a is this still an issue for you?