In order to give items to someone, or just drop on the ground, I have to use Q, or put them in my crafting grid, I cannot hold the item off to the side and click to through it on the ground. I just updated to 1.4.5 last night and that is when I first got the problem.
EDIT: It does this on both SMP and Single Player
Duplicate of MC-3181 , please use the search function to see if your bug has already been submitted. Currently over 30% of tickets are being closed as duplicate.