As soon as I join my server, I get a ton of "unable to locate sign" spam, and 95% of blocks are rendered as air. Doesn't happen in singleplayer, though, even with the exact same world.
Environment
Windows 7 Ultimate x64 SP 1, Pentium Dual-Core E5700 CPU, 4 GB RAM, Radeon HD 5450 GPU with 1 GB VRAM
MC-58881