If a mob attacks you while you’re looking in a chest the game will exit you out of the chest and not allow you to fight back, move at all, open your inventory, or even pause the game. It seemingly opens the emote wheel, it doesn't actually show the emote wheel, but the button menus appear for it on the side. If/when the mob kills you, you still cannot move, interact with anything, or pause the game once you respawn. The only fix I have found is force closing the game and restarting it.