After applying the effect command with health boost. If using the amplifier at 128 or higher you get a significantly large increase in heart containers, as opposed to the negative value you're supposed to get.
Environment
Windows 10 64-bit, AMD FX-6300 Six Core Processor, 8GB RAM, GeForce GTX 750 Ti, Java 1.8.0_73
Amplifiers beyond 4 are not supported.