I did some testing stuff on Minecraft 1.10.2 and 16w33a, but when I tested something to do with potions, I drank a Poison Potion, but when the Potion effect was done, the particles that play when a potion is in effect did not go away. I even tried drinking Milk, the particles were still there. I tried drinking the potion again and drank Milk, but the potion particles just didn't stop. I exited the world and then opened it again, but the potion particles were still there. I had to close the game, then open the game again to fix it. For some reason this didn't happen in Snapshot 16w32b, and it didn't happen on any servers.
Cannot reproduce.