As stated above if you play music from a Jukebox in 1.21 if you lower your jukebox/noteblock volume to 0% if mutes the sound from the jukebox and putting it back up to 100% still has the sound muted, only way to get it to play again is to take the disc out and put it back in
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Jarl-Penguin
Thank you for your report!
We're tracking this issue in MC-103511, so this ticket is being resolved and linked as a duplicate.
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Along with this, if you spam a jukebox with multiple music discs, some of them continue playing even if you take the disc out, and you can play discs ontop of each other. This is still an issue as of 1.21