Entities such as Animals, despawn when they aren't supposed to despawn, animals such as donkeys, pandas, foxes, cows, sheep, pigs, rabbits, chickens, horses, skeleton horses, mules, parrots, cats, wolves, ect. weather they are domestic animals or not, they despawn in cases where they should not despawn.
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GoldenHelmet
migrated
here is an example, i had at one point a skeleton horse, mule and donkey, all of which had nametags and were in small enclosed spaces, small enough to prevent despawning, however they still despawned when they were tamed domestic animals, this was not an issue untill after the nether update.
migrated
similarly, i also had a tamed fox, as tamed as one can get a fox, and it too despawned. As well as a few cats and parrots also despawned even being tamed.
migrated
The only thing i can think of that might be causing this issue, is the same thing that was patched before, when an entity is standing between 2 or more chunks and has a small chance to be deleted if the chunks do not load at the same time.
GoldenHelmet
Yes, it sounds like more cases of the random despawns. Thanks for the additional information. This ticket will be resolved as a duplicate of MCPE-21416.
Please clarify what you mean by “cases where they should not despawn” and provide precise steps to reproduce the unexpected behavior.