I am having this same issue. I am playing with one screen. When I move my mouse to change directions/view, the cursor will often appear at the task bar or controls at the top right of the screen. This has resulted in me clicking and minimising the tab, closing it, or opening another app. It is like the cursor is behaving how it does on a web page page, not how it should in-game where you “don’t have a cursor”, just the central cross hairs.
This exact same thing is happening to me! Glad I’m not the only one!