for me the culprit was overwolf, it still hasn't got the perfomance i have on 1.16, but at least now it's playable.
Was able to reproduce in 21w19a. the attachments include the log, a forced f3 crash, and an f3 screenshot.
Same bug on my machine.
for me the culprit was overwolf, it still hasn't got the perfomance i have on 1.16, but at least now it's playable.