I've had the same issue starting on 1.16.201. I use a single monitor and even when I don't have another game running, it still goes out every time. When I click though, it doesn't pause the game but instead clicks on whatever my mouse was over.
Its been about a year and a half, and it's still not updated. What gives?
I didn't see the older comments, but I was going back to them just now. I found a ton of them said to change UAC notification settings to the default one, so I did and now it's magically fixed! Hope this will help anyone who sees this comment.