If you bind F6 to any of the affected key binds below and then press F3 + F6, the Debug Options screen fails to open.
Affected key binds
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MC-300293
Debug Options screen (F3 + F6) can't be opened if certain key binds are bound to F6
Open
4
216fd76053f04a95bba4a54794b9926b
(Unassigned)
Community Consensus
Platform
Normal
Input
25w31a, 25w33a, 25w34b, 25w35a, 25w36b, ..., 1.21.9, 1.21.10, 25w41a, 25w43a, 25w44a
Retrieved
Can confirm.